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GHK Enhances
Mesenchymal Stem Cells
Acta Biomaterialia (2019)
Antibacterial GHK-Cu
Nanoparticles for
Wound Healing
Particle & Particle (2019)
Effect of GHK-Cu
on Stem Cells and
Relevant Genes
OBM Geriatrics
GHK Alleviates
Neuronal Apoptosis Due
to Brain Hemorrhage
Frontiers in Neuroscience
Endogenous Antioxidant
International Journal of Pathophysiology and Pharmacology (2018)
Regenerative and
Protective Actions of
GHK-Cu Peptide
International Journal of
Molecular Sciences
Skin Regenerative and
Anti-Cancer Actions
of Copper Peptides
GHK-Cu Accelerates
Scald Wound Healing
Promoting Angiogenesis
Wound Repair and

GHK Peptide Inhibits
Pulmonary Fibrosis
by Suppressing TGF-β1
Frontiers in Pharmacology
Skin Cancer Therapy
with Copper Peptides
The Effect of Human
Peptide GHK Relevant to
Nervous System Function
and Cognitive Decline
Brain Sciences (2017)
Effects of Tripeptide
GHK in Pain-Induced
Aggressive Behavior
Bulletin of Experimental
Biology & Medicine
GHK-Cu Elicits
In Vitro Alterations
in Extracellular Matrix
Am Journal of Respiratory
and Critical Care Medicine

Selected Biomarkers &
Copper Compounds
Scientific Reports

GHK-Cu on Collagen,
Elastin, and Facial Wrinkles
Journal of Aging Science
Tri-Peptide GHK-Cu
and Acute Lung Injury

Effect of GHK Peptide
on Pain Sensitivity

New Data of the
and TriPeptide GHK
SOFW Journal
GHK Peptide as a
Natural Modulator of
Multiple Cellular Pathways
in Skin Regeneration
BioMed Research (2015)
Resetting Skin Genome
Back to Health
Naturally with GHK
Textbook of Aging Skin
GHK-Cu May Prevent
Oxidative Stress in Skin
by Regulating Copper and
Modifying Expression of
Numerous Antioxidant Genes Cosmetics (2015)
GHK Increases
TGF-β1 in
Human Fibroblasts

Acta Poloniae

The Human Skin Remodeling Peptide Induces Anti-Cancer
Expression and DNA Repair Analytical Oncology
Resetting the
Human Genome to Health
BioMed Research
Enhanced Tropic Factor Secretion of Mesenchymal
Stem Cells with GHK
Acta Biomater
Anxiolytic (Anti-Anxiety)
Effects of GHK Peptide
Bulletin of Experimental
Biology & Medicine
Lung Destruction and
its Reversal by GHK
Genome Medicine
TriPeptide GHK Induces
Programmed Cell Death
of Neuroblastoma
Journal of Biotechnology
Stem Cell
Recovering Effect
of GHK in Skin
Peptide Science
Skin Penetration of
Copper Tripeptide in Vitro
Journal of International
Inflammation Research
Possible Therapeutics
for Colorectal Cancer
Journal of Clinical and
Experimental Metastasis
Methods of Controlling
Differentiation and
Proliferation of Stem Cells
Effects of
Copper Tripeptide
on Irradiated Fibroblasts
American Medical Association
Avoid Buying Fake Copper Peptides Dangerous

By Loren Pickart, PhD


This information is for the use of medical researchers and persons interested in health sciences. It must be emphasized that GHK and other copper binding peptides have not been tested and approved for the treatment of human diseases.

The primary cause of human aging and its attendant diseases are changes in the activity of the human genome. During aging there is an increase in the activity of inflammatory, cancer promoting, and tissue destructive genes plus a decrease in the activity of regenerative and reparative genes.

Regenerative copper peptides appear to help maintain wellness and youth. The human peptide GHK induces a plethora of health associated actions such as tissue repair, anti-inflammatory actions, anti-cancer effects, anti-infection, stem cell activation, increasing protein P63, and so on. Gene data from the Broad Institute indicates that GHK controls or strongly influences 31.8% of the human genes - increasing the output in 59%, and reducing it in 41%, of the genes.

In 2010, The Broad's Connectivity Map predicted that GHK, at a low and non-toxic level, would reverse the effects of aggressive, metastatic human colon cancer on 38 critical cancer-spreading genes. Specifically, it found that the cancer was suppressing genes used to kill cancer cells; the programmed cell death apoptosis system. Cells have "checkpoints" to determine if DNA is made properly and if it is not, the programmed cell death system terminates the cell. Recently, it was found that GHK did not harm certain normal cells, but acted reset the programmed cell death in human cancer cells and inhibit their growth. GHK-Cancer

In 2012, the Connectivity Map indicated that GHK would shift the gene output in severe emphysema in chronic obstructive lung disease (COPD) and shut down tissue destructive genes while increasing the output of genes associated with tissue healing and remodeling. This prediction was confirmed when tested on cells from patients with the disease where GHK, at a very low and non-toxic level, shifted the cellular genes patterns from tissue destruction to tissue repair. GHK-Emphysema

The Holy Grail of genome research is resetting the genes for health. GHK appears to do this on a wide range of tissues and diseases. Since GHK was originally isolated as a factor high in young persons but that declines with age, it is also possible that the molecule might restore humans to a biologically younger state.

Featured Topics

About Dr. Pickart

how the STORY OF MY LIFE affects you and your family

Combined Topics

1. Published Studies on Tissue and Skin Remodeling Copper Peptides

2. General Biology of Human Skin

Copper Peptide Experiments and References

2.1 Background Work on Copper Peptides

2.2 published articles & presentations

2.3 In the Human Body

2.4 Aging Reversal Experiments

2.5 The Copper Switch

2.5.1 Similarities & receptors for albumin-cu, GHK-Cu, and dips-Salicylate-cu

2.6 Skin Renewal Cycle

2.6.1 GHK's control of stem cells

2.7 Cosmetic Skin Remodeling

2.71 Copper Peptide Aging Reversal Clinical Studies

2.8 With Laser and LED Lights

2.9 Wound Healing

2.9.1 Wound Healing in horses and dogs



2.9.4 GHK and Infection Protection

2.9.5 GHK and dna repair

2.10 Skin and Hair Transplantation

2.11 Copper Peptides: Anti-oxidant and Anti-inflammatory Activities

2.12 Hair Growth

2.13 Hair follicles and skin remodeling

2.14 Stopping Hair Loss After Chemotherapy

2.15 Bone Healing

2.16 Suppression of Cancer Tumors and Cancer Metastasis Genes

2.17 Stomach and Intestinal Healing

2.18 Liver Regeneration

2.19 Nerve Regeneration

2.191 Combined Wound Healing, Anti-PAIN, AND ANTI-ANXIETY EFFECTS

2.192 GHK and ups (Ubiquitin Proteasome system)

2.20 Blocking of UV damage to Skin Cells

2.21 Fingernail Growth

2.22 Organ Regeneration

2.23 Tissue Regeneration Biochemistry

2.24 Chemistry

2.25 Need for Improved Copper Peptides

2.26 Future Uses

3. A Possible Mechanism Whereby Skin Remodeling May Suppress Cancer Metastasis Genes - Wound Healing Society - 2011

4. Breakdown Resistant Copper Peptides with Improved Healing Actions - Wound Healing Society - 2009

5. GHK Defines the Biochemical Reactions of Tissue Remodeling - Wound Healing Society 2008

6. Improving Hair Growth with Skin Remodeling Copper Peptides - Cosmetics & Medicine (Russia) 2004 and Body Language Dermatology (United Kingdom) 2004

7. Skin Remodeling with Copper Peptides - Cosmetics & Medicine (Russia) 2004

8. nutrients that turn back the clock - Bypassing confusion and food wars

9. methods and compositions for increasing skin remodeling US paten 8,184,204

10. THE ESSENTIALS OF COPPER: Your Body’s Protective and Anti-Aging Metal

11. Science references

We will be loading many more articles over the next few weeks.

Questions or Advice?

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Alternate Email:

Call us at 1-800-405-1912 Monday through Friday (8 am to 6 pm) PST

1994 - 2019

No Reproduction without Explicit Permission by loren pickart, Phd