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New Articles and Information
Needling and Rollers for Scar Reduction by Dr. Phillipa McCaffery
Visit Our NEW Unified Website at ReverseSkinAging.com

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Anti Aging Facial Skin Care: Gentle, Mild and Safe

Skin Biology’s remodeling copper peptides have been proven gentle, safe and effective in numerous clinical studies published in international dermatology journals. There is no other cosmetic skin renewal product that can demonstrate this level of independent published evidence to prove its effectiveness. For those concerned about copper absorption, very little copper from our products penetrates the skin. However, tissue copper is not harmful. In fact, numerous studies are finding that higher tissue copper protects against many diseases of aging.

See Copper Safety & Degenerative Disease Reduction
 

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How Skin Remodeling Copper Peptides Improve Reverse Skin Aging

Healthful Actions acts by:	Effect on Skin:
Anti-inflammatory and anti-oxidant • Boosts the skin's anti-oxidant defenses by increasing copper into superoxide dismutase • Decreases production of TGF-beta, the scar forming protein • Blocks dermal damage by interleukin-1 and TNF-alpha	• Calmer skin  • Less irritation  • Reduced scarring
• Removes damaged skin and proteins • Activate metalloproteinases	• Clear radiant complexion free of blemishes and bumps
• Rebuilds skin • Supports the synthesis of new collagen and elastin • Helps fibroblasts contract collagen strands for a tighter epidermis • Increases keratinocyte production • Helps increase water-holding proteoglycans	• Firmer skin with increased elasticity • Reduced wrinkles • Smoother complexion • Enhanced moisturization
• Revs up the blood's microcirculation	• Vital nutrients provide a youthful glow
• Repairs, thickens, and tightens skin barrier	• Less skin evaporation keeps skin dewy and moist • Healthy barrier that resists viruses and bacteria
• Enlarges size of small (nearly invisible) vellus hair follicles that produce stem cells for skin	• Increased stem cells nourish the skin

Effect of Higher Tissue Copper Levels
Very little copper from SRCPs penetrates the skin but higher tissue copper levels have strong actions that reverse many of the the condition of aging.
Click here to see our page on: Copper and Health 

Higher Tissue Copper Levels

1. Reduce oxidative damage in tissues

2. Diminish protein crosslinking and glycation

3. Raise pain reducing enkephalins or "happiness hormones"

4. Improve immune system function

5. Raise DHEA levels, metabolism, and sex hormones

6. Increase neurohormones that raise mental alertness

7. May protect against Alzheimer's disease

 

"The real sin against life is
to abuse and destroy beauty,
even one's own - even more one's own,
for that has been put in our care and
we are responsible for its well-being."
 -Katherine Anne Porter 

Best Face Products to Get the Skin of a Babe

Have you ever wondered why babies have such beautiful skin? When we are children, our skin naturally remodels and renews itself unveiling a youthful glow. Remodeling plays the most crucial role of skincare, the Sine Non Qua (that which cannot be done without). Remodeling is the cycle of renewal that removes older skin, scars, blemishes, and damaged proteins while replacing them with a new, younger complexion. However, as we age, this process slows down and produces a dry, wrinkled, inelastic skin populated by unsightly lesions. Remodeling offers a mechanism of repair that removes damaged materials from the skin and creates new, tight, blemish-free skin.

Beyond Retinoic Acid - The Natural Human Signals for Skin Remodeling

Retinoic acid (retin-A), the first widely used product to remodel skin, reduces fine lines – but at a price. This highly acidic product unleashes some unpleasant side effects such as chronic irritation and redness. When Dr. Loren Pickart discovered Skin Remodeling Copper Peptides (SRCPs), he found that these natural molecules signal the skin to reduce wrinkles without irritation. They increase the skin's internal water-holding proteins which moisturize skin. Clinical studies have found SRCPs more effective in restoring the skin's collagen than Vitamin C or retin-A. Collagen and elastin are rebuilt, giving you a firmer, more elastic skin. The advantage of these peptides over retin-A is that they are non-irritating and possess strong anti-inflammatory properties. In every comparative clinical study, skin remodeling copper peptides have proved superior to Retin-A(R), Vitamin C creams, and Kinerase(R) in terms of reducing wrinkles, blotchiness and improving firmness. SRCPs also help activate your skin's system to remove damaged collagen, elastin and reduce the skin's production of the scar-producing factor, TGF-beta.

Skin Renewal Boosters by Dr. Loren Pickart

Skin Biology's new and patented Second Generation Copper-Peptides are breakdown-resistant, long acting, and produce strong skin regeneration and remodeling. They work synergistically with hydroxy acids and Retin-A for enhanced rejuvenation. In contrast, the single peptides (tripeptides or pentapeptides) in many cosmetics tend to be fragile, short-acting, and cannot be used with hydroxy acids. Extensive safety testing has proven Skin Biology's Copper-Peptides to be non-allergenic and non-irritating. They have neither the allergenic sensitization problems of the bacterial produced Copper-Peptides nor the biological inactivity of copper complexes ("colorless-copper") used by some cosmetic companies. Microbiological studies of Skin Biology products have found them to inhibit the growth of dangerous, pathogenic skin bacteria.

What To Expect

Watch copper peptides turn back the clock on skin aging!

In a week - Skin color and "glow" improves as the blood capillary network is rebuilt. Lifeless and graying skin regains the rosy glow of youth.

In a month – Skin becomes better moisturized as the skin barrier tightens and the water-holding proteins (proteoglycans) increase. Many of our customers tell us they no longer need moisturizers. Skin firms and tightens as new collagen and elastin replaces old damaged proteins. The skin slowly thickens and appears much younger and more resilient.

Over several months - Skin lesions and scars slowly vanish while wrinkles are reduced. The result is a younger-looking, smoother, blemish-free skin. This process can be hastened by applying hydroxy acids to speed exfoliation. Clear, blemish-free skin is the number one factor in interpersonal attraction based on psychological studies of 170 human cultures.

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Exclusively from Skin Biology

These new improved, breakdown resistant Copper-Peptides are available exclusively in Skin Biology products. Five US patents  have been granted to Skin Biology for the exclusive use of this technology (US 5,698,184, US 5,382,431, 5,858,993, US 5,888,522, US 5,554,375, and pending patents).
 

Caution - Not All Copper-Peptides Remodel Skin

Although you may find other companies selling Copper-Peptide products, our tests reveal they provide little or at best marginal activity. In fact, there are peptide cosmetics that actually inhibit skin repair. Some contain peptides derived from yeast or bacteria that can cause skin allergies and asthma. Many companies marketing harmful forms of copper peptides have been fined repeatedly by the US Federal Trade Commission for false advertising. "Clinically proven" is a meaningless advertising slogan that can imply virtually anything. For more information on various Copper-Peptides, please visit: Comparing Copper-Peptides

Distinguishing Between Remodeling Copper-Peptides, Aminopeptides, and Pentapeptides

Many peptide products claim to improve skin by increasing the production of collagen, elastin, and proteoglycans. Manufacturers state these peptides act much like Transforming Factor Beta-1 (TGF-beta 1). TGF-beta 1 and peptides with similar actions were intensively tested in wound healing studies about ten years ago. Such peptides failed because, while they rapidly healed wounds, they also produced heavy and unacceptable scarring. If you use these new peptides, be cautious. We have received several reports indicating hard spots on the skin or lumps under the skin after a month of using these products. With TGF beta, there were further concerns over potential side effects. TGF-beta-1 can make normal cells grow like cancer cells and may speed the growth of breast cancer. It also may play a role in the development of kidney failure. See Comparing Copper-Peptides.

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Remodeling Copper Peptides vs
Aminopeptides and Pentapeptides

Skin Remodeling Copper Peptides	Aminopeptides and Pentapeptides
Increase collagen, elastin, proteoglycans - Yes	Yes
Activate removal of damaged proteins and older skin - Yes	No
Effect on TGF-beta (scar forming and skin hardening hormone): Suppresses formation of TGF beta	Said to similar in action to TGF beta
Effect on Interleukin-1 (skin damaging cytokine): Blocks Interleukin-1 damage on cells	No effect
Powerful antioxidant actions against oxygen radicals	No antioxidant actions
Naturally present in the human body - Yes; present in human blood at 200 micrograms per liter	No, not normally present
Cell Protectant: Aids the growth and survival of many types of mammalian cells in culture	No

Proposed Biochemical Mechanism of Skin Remodeling, Scar Reduction, and Hair Follicle Enlargement

The following diagram is based on GHK-copper(II) actions. See Published Articles on SRCPs. Newer Skin Biology skin remodeling copper peptides act similarly but are composed of less fragile peptides that also have a better adherence to the skin.
 

	"Beauty is a Form of Genius -- is higher, indeed, than genius, as it needs no explanation. It is of the great facts in the world like sunlight, or springtime, or the reflection in dark water of that silver shell we call the moon." -Vicomte de Valmont, Les Liaisons Dangereuses
"Que tu me plais dans cette robe, qui te deshabille si bien..." Theophile Gautier 1811-1872 "How you please me in that dress that undresses you so well ..."

Iamin Gel Wound Dressing®, Iamin Impregnated Gauze Dressing®, OsmoCyte® PCA Pillow, Iamin Wet Dressing (copper-saline)®, Iamin-2 Hydrating Gel®, Iamin-Vet®, GraftCyte® Advanced Hair Restoration Technology, GraftCyte® Moist Dressings, GraftCyte® Hydrating Mist, GraftCyte® Post-Surgical Shampoo & Conditioner, GraftCyte® Head Start Single Patient Pack, Tricomin® Solution Follicle Therapy Spray, Tricomin® Revitalizing Shampoo, Tricomin® Restructuring Conditioner and Tricomin® Conditioning Shampoo, Complex Cu3® Intensive Tissue Repair Cream, Complex Cu3® Hydrating Gel, Complex Cu3® Gentle Face Cleanser, Iamin-IB®, Neova®, are trademarks of ProCyte Corporation and marketed by ProCyte and Bard Medical. Blue Copper Firming Elasticity Repair®, Climate Extreme Body Repair®, and Blue Razor Aftershave®, are  products and trademarks of Osmotics Inc. Propecia® is a trademark of Merck Pharmaceuticals. . Biopeptide-CL is a trademark of Sederma. A-Copper Moisturizer is a trademark of Serious Skin Care. Kinerase(TM) is a product and trademark of ICN Corporation. Neutrogena Visibly Firm Night Cream®, and  Neutrogena Visibly Firm Eye Cream® are products and trademarks of the Neutrogena Company.

Aging Reversal Sciences, Reverse Skin Aging, Skin Biology, CP Serum, CP Night Eyes, CP Feet, CP Nails, BioHeal, Folligen, TriReduction, Calypso's Oil, Protect & Restore, Copper Beauty, and "Copper Peptides - Your Skin's 911 Call!", Copperceuticals, and "Loren Pickart Copperceuticals" are trademarks of Skin Biology, Inc.

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